Direct numerical simulations are combined with two-way coupled Lagrangian point particles to study the effect of Reynolds number on particle-turbulence interaction. Turbulent planar Couette flow is simulated at a constant dispersed phase mass loading of ϕ m = 0.25 for particle Stokes numbers of St K = [O(1), O(10), O(100)] (based on the Stokes time scale of the particle and the Kolmogorov time scale of the flow) and bulk Reynolds numbers of Re b = [8100, 24000, 72000] (based on the plate velocity difference and separation distance). Statistics of swirling strength \λ ci \ are used to evaluate the impact of particles on near-wall motions which are responsible for turbulent, wall-normal momentum transport. Instantaneously, the number of high-strength swirling motions near the wall decreases significantly in the presence of particles, and this trend is enhanced with increasing Re b . Conditional averages are computed using linear stochastic estimation, providing the average structures responsible for ejection events near the wall. These conditional eddies are weakened substantially by the presence of the dispersed phase, and this effect is again enhanced with increasing Re b . We propose a mechanism where particles, by interfering with the hairpin regeneration process near the wall, can influence turbulent fluxes in a way that increases with Re b despite only having direct interaction with scales on the same order as their small physical size. At the same time, turbulent momentum flux concentrated at higher wavenumbers with increasing Re b allows small particles to be effective agents for altering turbulent transport.